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Medizinische Fakultät Zentrum für Biochemie

Publikationen

Ausgewählte Publikationen

  1. Hanisch, F.G. (2022) Recombinant norovirus capsid protein VP1 (GII.4) expressed in H5 insect cells exhibits post-translational modifications with potential impact on lectin activity and vaccine design. Glycobiology [Epub ahead of print]
  2. Morcos, Y.A.T., Lütke, S., Tenbieg, A., Hanisch, F.G., Pryymachuk, G., Piekarek, N., Hoffmann, T., Keller, T., Janoschek, R., Niehoff, A., Zaucke, F., Dötsch, J., Hucklenbruch-Rother, E., and Sengle, G. (2022) Sensitive asprosin detection in clinical samples reveals serum/saliva correlation and indicates cartilage as source for serum asprosin. Sci Rep.  12:1340
  3. Hanisch, F.G., Aydogan, C., and Schroten, H. (2021) Fucoidan and Derived Oligo-Fucoses: Structural Features with Relevance in Competitive Inhibition of Gastrointestinal Norovirus Binding. Mar Drugs. 19
  4. Hanisch, F.G., and Kunz, C. (2021) Novel Class of Human Milk Oligosaccharides Based on 6'-Galactosyllactose Containing N-Acetylglucosamine Branches Extended by Oligogalactoses. J Proteome Res. 20:3865-3874
  5. Pottie, L., Van Gool, W., Vanhooydonck, M., Hanisch, F.G., Goeminne, G., Rajkovic, A., Coucke, P., Sips, P., and Callewaert, B. (2021) Loss of zebrafish atp6v1e1b, encoding a subunit of vacuolar ATPase, recapitulates human ARCL type 2C syndrome and identifies multiple pathobiological signatures. PLoS Genet. 17:e1009603
  6. Wiatr, M., Staubach, S., Figueiredo, R., Stump-Guthier, C., Ishikawa, H., Schwerk, C., Schroten, H., Hanisch, F.G., Rudolph, H., and Tenenbaum, T. (2020) Echovirus-30 Infection Alters Host Proteins in Lipid Rafts at the Cerebrospinal Fluid Barrier In Vitro. Microorganisms 8
  7. Derya, S.M., Spiegel, H., Hanisch, F.G., Morozov, V., Schroten, H., Jennewein, S., and Parschat, K. (2020) Biotechnologically produced fucosylated oligosaccharides inhibit the binding of human noroviruses to their natural receptors. J Biotechnol.  318:31-38
  8. Janes, V., Grabany, S., Delbrouck, J., Vincent, S.P., Gottschalk, J., Elling, L., and Hanisch, F.G. (2020) Fluorinated Galactoses Inhibit Galactose-1-Phosphate Uridyltransferase and Metabolically Induce Galactosemia-like Phenotypes in HEK-293 Cells. Cells. 9:607.
  9. Hanisch, F.G., Hansman, G.S., Morozov, V., Kunz, C., and Schroten, H. (2018) Avidity of a-fucose on human milk oligosaccharides and blood group-unrelated oligo/polyfucoses is essential for potent norovirus-binding targets. J. Biol. Chem. 293, 11955-11965.
  10. Staubach, S., Wenzel, A., Beck, B.B., Rinschen, M.M., Müller, S., and Hanisch, F.G. (2018) Autosomal Tubulointerstitial Kidney Disease-MUC1 Type: Differential proteomics suggests that mutated MUC1 (insC) affects vesicular transport in renal epithelial cells. Proteomics. 18, e1700456.
  11. Wenzel, A., Altmueller, J., Ekici, A.B., Popp, B., Stueber, K., Thiele, H., Pannes, A., Staubach, S., Salido, E., Nuernberg, P., Reinhardt, R., Reis, A., Rump, P., Hanisch, F.G., Wolf, M.T.F., Wiesener, M., Huettel, B., and Beck, B.B. (2018) Single molecule real time sequencing in ADTKD-MUC1 allows complete assembly of the VNTR and exact positioning of causative mutations. Sci Rep. 8, 4170
  12. Staubach, S., Müller, S., Pekmez, M., and Hanisch, F.G. (2017) Classical galactosemia: Insight into molecular pathomechanisms by differential membrane proteomics of fibroblasts under galactose stress. J. Proteome Res. 16, 516-527.
  13. Chalick, M., Jacobi, O., Pichinuk, E., Garbar, C., Bensussan, A., Meeker, A., Ziv, R., Zehavi, T., Smorodinsky, N.I., Hilkens, J., Hanisch, F.G., Rubinstein, D.B., and Wreschner, D.H. (2016) MUC1-ARF-A novel MUC1 protein that resides in the nucleaus and is expressed by alternative reading frame translation of MUC1 mRNA. PLoS One 11, e0165031
  14. Schroten, H., Hanisch, F.G., and Hansmann, G.S. (2016) Human norovirus interactions with histo-blood group antigens and human milk oligosaccharides. J. Virol. 90, 5855-5859
  15. Staubach, S., Pekmez, M., and Hanisch, F.G. (2016) Differential proteomics of urinary exovesicles from classical galactosemic patients reveals subclinical kidney insufficiency. J. Proteome Res. 15, 1754-1761
  16. Bonar, D., and Hanisch, F.G. (2014) Trefoil Factor Family domains represent highly efficient conformational determinants for N-linked N,N'-di-N-acetyllactosediamine (LacdiNAc) synthesis. J. Biol. Chem. 289, 29677-29690
  17. Hanisch, F.G., Bonar, D., Schloerer, N., and Schroten, H. (2014) Human Trefoil Factor 2 is a lectin that binds α-GlcNAc-capped mucin glycans with antibiotic activity against Helicobacter pylori. J. Biol. Chem. 289, 27363-27375