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Interactions between cells and the extracellular matrix

Modulation of cellular activities by laminin isoforms.

Laminin-binding integrins and other receptors in the control of epithelial cell migration.

The role of laminins in the formation and the remodeling of the epithelial basement membrane.

Fig. 2: Cultivated human primary keratinocytes (green) have deposited and organized large amounts of laminin 332 (red)

Fig. 3: At the basal surface of healthy keratinocytes α6β4 integrins (red) are well organized (A) while they are randomly dispersed for keratinocytes lacking an important component (kindlin) of their adhesion complex (B)

AG Aumailley